Introduction: What makes a Sporting Icon?

Introduction: What makes an antipsychotic atypical?

T spectives on this issue tend to define this term differently. To a pharmacologist, it can mean “serotonin-2A (5-HT2A)–dopamine-2 (D2) antagonist” or “multiple simultaneous neurotransmitter binding activities.” To a prescriber, it can mean “low extrapyramidal symptoms” or “reduction of negative symptoms.” To a marketeer, it may mean “new and different.” To a formulary committee with a short-te...

What makes champions? A review of the relative contribution of genes and training to sporting success.

Elite sporting performance results from the combination of innumerable factors, which interact with one another in a poorly understood but complex manner to mould a talented athlete into a champion. Within the field of sports science, elite performance is understood to be the result of both training and genetic factors. However, the extent to which champions are born or made is a question that ...

Introduction to a special series: What Makes Man Human

One of the most pressing and timely scientific questions concerns the evolution of man. In 1970, Karl Pribram delivered the James Arthur Lecture at the American Museum of Natural History in New York City. His lecture, "What Makes Man Human," was one of the most eloquent and brilliant syntheses of this problem ever made. The Journal is proud to publish this Lecture for the first time in an open ...

Polymeric Gas Separation Membranes: What Makes them Industrially more Attractive?

What Makes a Revolution

Although property rights are the cornerstone of capitalist economies, throughout history existing claims have been frequently overturned and redefined by revolution. A fundamental question for economists is what makes revolutions more likely to occur. A large literature has found contradictory evidence for the effect of income and income inequality on revolt, possibly due to omitted variable bi...